(S)-Verapamil hydrochloride
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产品名称:
(S)-Verapamil hydrochloride
产品型号:
GOY-Y1885
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-25
简单介绍
(S)-Verapamil hydrochlorideN/A
(S)-Verapamil hydrochloride
的详细介绍
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性能参数
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产品名称
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(S)-Verapamil hydrochloride
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规格
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5mg 10mg 25mg 50mg 100mg
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货号
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GOY-Y1885
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含量
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>98.00%
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CAS
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36622-28-3
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别名
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N/A
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化学名
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N/A
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分子式
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C27H39ClN2O4
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分子量
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分子 491.06
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溶解度
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N/A
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储存条件
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N/A
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1].
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) not the (R)-Verapamil hydrochloride potently induces the death of MRP1-transfected BHK-21 cells[1]. (S)-Verapamil hydrochloride is good active form and has the low bioavailability[1].
[1]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22. [2]. Tannergren C, et al. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther. 2004 Apr;75(4):298-309.
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