性能参数

产品名称

Ac-YVAD-CMK

规格

500μg 1mg 5mg 10mg

货号

GOY-Y1868

 含量

>98.00%

CAS

178603-78-6

别名

N/A

化学名

N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxo-propyl]-L-alaninamide

分子式

C24H33ClN4O8

分子量

分子 541

溶解度

20mg/mL in DMSO, 10mg/mL in DMF

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Ac-YVAD-CMK is a selective, irreversible inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Ac-YVAD-CMK is neuroprotective in a rat model of cerebral ischemia.[1]

Reference:

[1]. Rabuffetti, M., Sciorati, C., Tarozzo, G., et al. Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. Journal of Neuroscience 20, 4398-4404 (2000).

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