性能参数

产品名称

(S)-nitro-Blebbistatin

规格

1mg 5mg 10mg 25mg

货号

GOY-Y1858

 含量

>98.00%

CAS

856925-75-2

别名

N/A

化学名

N/A

分子式

C17H13N3O4

分子量

分子 323.3

溶解度

DMF: 16 mg/ml,DMSO: 16 mg/ml,DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

(S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin , which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (-)-Blebbistatin rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 μM), while poorly inhibiting smooth muscle myosin (IC50 = 80 μM). Through these effects, it blocks apoptosis-related bleb formation, directed cell migration, and cytokinesis in vertebrate cells. However, prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. The addition of a nitro group stabilizes the molecule to circumvent its degradation by prolonged blue light exposure. (S)-nitro-Blebbistatin has the same stereochemistry as the active (-)-blebbistatin enantiomer.

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N(Α)-苄氧羰基-D-组氨酸  98%  噻螨酮标准溶液 10μg/ml,u=6%

H-His(Trt)-2-Chlorotrityl Resin 0.3~0.8 mmol/g, 100~200 mesh  七氯标准溶液 100μg/ml,u=2（剧毒品）

Fmoc-His(Trt)-Wang resin 100-200 mesh, 1%DVB  七氯标准溶液 10μg/ml,u=3%（剧毒品）

Fmoc-D-His(Trt?

BRD7-IN-15mg  10mg 50mg 100mg>98.00%Cas No. N/AC22H28Cl2N4O3

BRD4884500μg  1mg 5mg 10mg>98.00%Cas No. 1404559-91-6C18H19FN2O2

BRD4 degrader AT15mg  10mg 25mg 50mg>98.00%Cas No. 2098836-45-2C48H58ClN9O5S3

CAY107221mg  5mg 10mg 25mg>98.00%Cas No. 388086-13-3C21H14Cl2N2O2

CAY107211mg  5mg 10mg 25mg>98.00%Cas No. 848688-62-0C18H13N3O3S