性能参数

产品名称

β-Elemonic Acid

规格

1mg 5mg 10mg 25mg

货号

GOY-Y1854

 含量

>98.00%

CAS

28282-25-9

别名

N/A

化学名

N/A

分子式

C30H46O3

分子量

分子 454.7

溶解度

DMF: 30 mg/ml,DMF:PBS (pH 7.2)(1:3): 0.25 mg/ml,DMSO: 5 mg/ml,Ethanol: 5 mg/ml

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

β-Elemonic acid is a triterpene isolated from Boswellia (Burseraceae) that exhibits anticancer activity. It inhibits growth of non-small cell lung cancer (NSCLC) A549 cells (IC50 = 6.92 μM) in vitro. β-Elemonic acid induces apoptosis and cytotoxicity in A549 cells in a dose-dependent manner but has no effect on normal epithelial WI-38 cells. It inhibits phosphorylation of p42/44, MAPK/JNK, and p38 and induces production of reactive oxygen species (ROS) and COX-2 expression in vitro. β-Elemonic acid also inhibits prolyl endopeptidase (IC50 = 39.74 μM) in vitro

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